Development and Validation of a Discriminating In Vitro Dissolution Method for Oral Formulations Containing Satranidazole

the development and validation of dissolution method for donepezil tablet

Development of Discriminating Dissolution Method for an Insoluble Drug: Nisoldipine

Nisoldipine is poorly soluble drug. There is no official dissolution method available in the literature or recommended by regulatory agencies. In present study dissolution method was developed. the media selection was done by solubility study of drug in different pH as well as in different surfactant solution. Volume of media was found by calculating sink condition. Sodium lauryl suphate, 1.0% ...

development and implementation of an optimized control strategy for induction machine in an electric vehicle

in the area of automotive engineering there is a tendency to more electrification of power train. in this work control of an induction machine for the application of electric vehicle is investigated. through the changing operating point of the machine, adapting the rotor magnetization current seems to be useful to increase the machines efficiency. in the literature there are many approaches wh...

Development of a Dissolution Method to Compare Tablet Formulations Containing Valsartan/Amlodipine

Dissolution profiles were developed in three different pH media for the evaluation of valsartan/amlodipine (VS/AM) release from tablets. The selection of the most appropriate dissolution method was based on the calculated similarity (f2) and dissimilarity (f1) values. A new HPLC method was developed to quantify VS/AM in tablets. The method was validated in accordance with international guidelin...

Development of Discriminatory Method for Dissolution of Carvedilol Marketed Formulations

Carvedilol (BCS Class II drug) is a nonselective β-adrenergic blocking agent with α1-blocking activity and it is mainly used in the management of hypertension. Two commercial brands of carvedilol drug, of strength 12.5mg were used for the Invitro dissolution studies. In the present study four dissolution media [pH 1.2 (0.1 N Hcl), pH 4.5 Acetate buffer, pH 6.8 phosphate buffer, and Distilled wa...